Clyde River National Park consists of gently to steeply sloping land on both sides of the Clyde River, as well as two islands. The park contains eight vegetation communities, including three endangered ecological communities - River Flat Eucalypt Forest, Swamp Oak Floodplain Forest and Coastal Saltmarsh. It supports populations of the vulnerable glossy black-cockatoo, masked owl and yellow-bellied glider, and the regionally rare rat’s tail orchid and elkhorn.
Several Aboriginal campsites and middens are known to occur and some areas of the park are reported to have been used traditionally for ceremonial, teaching and other purposes.
Clyde River National Park provides opportunities for viewing scenery and picnicking at Holmes Lookout, and bush camping, picnicking and fishing along the river.